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Welcome to the Hultgren Lab

The Hultgren lab is a highly collaborative group using diverse techniques, both within the lab and with many distinguished outside basic science and clinical researchers.

We are blending multiple scientific disciplines to elucidate bacterial and host mechanisms that determine the onset, course and outcome of interactions between the host urinary tract and bacterial pathogens.

Our work is changing the way UTIs are evaluated, re-shaping models of bacterial infections in general, and spawning development of novel vaccines and anti-microbial therapeutics to diagnose, treat and prevent UTIs and their sequelae.

Opportunities in the Hultgren Lab

Opportunities are available in our lab to study aspects of uropathogenesis in a dynamic interdisciplinary setting. Specifically, currently, opportunities are available in two broad areas of study: i) the assembly mechanisms of chaperone-usher-pathway (CUP) pili; and ii) the genomic and genetic diversity of E. coli responsible for the differing ability of E. coli isolates to cause urinary tract infections in diverse host backgrounds. Please apply by sending an email to hultgren@wustl.edu.
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